The transgenic construct contains (5' to 3') a human ubiquitin C (UB) gene promoter, a floxed STOP cassette (3 repeats of SV40 polyA stop sequence flanked by loxP sites), the mouse Pou5f1 coding sequence with a myc tag, T2A/furin ribosomal skip sequence, EGFP coding sequence, and a BGH poly(A) sequence. (J:236622)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count