Exon 2 and a neomycin selection cassette was deleted via Cre-mediated recombination of flanking loxP sites. Quantitative RT-PCR analysis confirmed the absence of mRNA expression in homozygous mutant brains. (J:224914)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count