The open coding region in exon 3 was replaced with the Tex11 open reading frame with a T to C point mutation that results in the amino acid substitution of alanine for valine at position 479 (V749A). This mutation corresponds to a mutation in sterile human males. Cre-mediated recombination removed the selection cassette inserted downstream of the inserted expressed sequence. (J:229429)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion, Intragenic deletion, Single point
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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