The open coding region in exon 3 was replaced with the Tex11 open reading frame with a T to A point mutation that results in the amino acid substitution of arginine for tryptophan at position 118. This mutation corresponds to a mutation in sterile human males. Cre-mediated recombination removed the selection cassette inserted downstream of the inserted expressed sequence. (J:229429)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count