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A construct was inserted between exons 1 and 2 of this locus that encodes the CAG promoter followed by a loxP flanked a B-geo-STOP cassette followed by a loxN site then a Tau-mTurquoise sequence and woodchuck hepatitis post-transcriptional regulatory element (WPRE) followed by a lox2272 then a loxN site followed by a Tau-tdTomato sequence immediately followed by an IRES and dominant negative Gnas sequence a WPRE and lox2272 site. This allele can be cre-induced to generate stochastic expression of either Tau-Turquoise alone or Tau-tdTomato along with the dominant negative GNAS. (J:233447)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
