A stop cassette flanked by loxP sites and the full-length sequence were inserted downstream of the promoter. Cre-mediated recombination is necessary to remove the stop cassette and express the inserted gene. (J:185303)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count