CRISPR/Cas9 technology replaced 65 kb downstream of exon 1 with an FRT-flanked neomycin resistance cassette with a 3' loxP site. Founders 3 (64,901 bp), 5 (64,918 bp) and 13 (64,918 bp) transmitted germline. (J:232970)
Basic Information
(C57BL/6 x DBA/2)F1 x C57BL/6J
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count