CRISPR/Cas9 technology replaced 65 kb downstream of exon 1 with an FRT-flanked neomycin resistance cassette with a 3' loxP site. Founders 3 (64,901 bp), 5 (64,918 bp) and 13 (64,918 bp) transmitted germline. (J:232970)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x DBA/2)F1 x C57BL/6J
Endonuclease-mediated
Insertion, Intragenic deletion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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