The CAG promotor, a loxP-flanked neo-stop cassette, the mouse cDNA and an FRT-flanked IRES2-AcGFP1-Nuc cassette were inserted in intron 1 of the locus. Cre expression is required to excise the neo-stop cassette and allow for expression of the gene and the nucleus-targeted GFP. Flp expression is required to remove the reporter cassette. (J:233595)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
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--
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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