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A 70kb fragment encomapssing the entire human HBB genomic locus, including the epsilon, gamma and beta genes, was used in a construct to generate transgenic mice. Four mouse lines were created, 2, 13, 15 and 72. Line 72 contains one copy number of the inserted sequence. (J:132056)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
