Out-of-frame exon 3 was flanked by loxP sites. Thus, if subjected to cre-mediated recombination, this exon would be deleted, creating a knock-out for the gene. (J:232825)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count