A tandem dimer tdTomato (TOM) gene lacking a transcriptional stop site was inserted immediately after and in-frame with the start ATG of exon 1. The resulting transcript codes for a chimeric peptide with the Tomato reporter N-terminal and Tox C-terminal. An FRT-flanked neo cassette that was also inserted was removed by flp-mediated recombination. (J:232838)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count