The construct targeting exon 4 consisted of a loxP site in intron 3 and a neo cassette (FRT-flanked pGK-gb2 Neo and a loxP site) in intron 4. Flp-mediated recombination removed the neo cassette, leaving a single FRT site and the loxP site behind. Exon 4 is floxed. (J:232839)
Basic Information
(C57BL/6NTac x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count