Log In|Sign Up
EN
Exon 6 was replaced with a modified one in which an A-to-T point mutation results in the amino acid substitution of tyrosine with phenylalanine at position 147 (p.Y147F). A loxP site flanked neomycin resistance gene cassette was inserted into intron 6. Quantitative real-time PCR analysis revealed normal mRNA levels in the cortex of P12-P17 homozygous mutant mice. (J:217014)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
