The gene was targeted with a vector containing a loxP site in intron 2 and an FRT-neo-FRT-loxP cassette in intron 6. Subsequent FLP-mediated recombination excised the neo cassette, leaving exons 3-6 floxed. (J:232813)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count