The construct inserted a three-frame triple stop codon cassette immediately downstream of the first codon in the exon 8 (ATG TAA A TAG A TGA), causing premature translation termination. A kanamycin-neomycin resistance gene cassette was inserted downstream of the stop codons. (J:229314)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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