Using a bacteria artificial chromosome (BAC), exon 3 of the gene was flanked with a loxP site and a Frt-Neo-Frt-loxP cassette. Flpe-mediated recombination removed the neo cassette. (J:233223)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count