An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 14. An additional loxP site was inserted downstream of exon 14. Flp-mediated recombination removed the selection cassette and left exon 14 floxed. Cre-mediated deletion of exon 14 produces a protein that contains the first 701 residues and 25 additional artificial residues. (J:199480)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count