A targeting vector was designed to insert a single loxP site upstream of exon 1, and a loxP-flanked neomycin resistance (neo) cassette downstream of exon 1. Cre-mediated recombination removed the neo cassette and exon 1. (J:211733)
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A targeting vector was designed to insert a single loxP site upstream of exon 1, and a loxP-flanked neomycin resistance (neo) cassette downstream of exon 1. Cre-mediated recombination removed the neo cassette and exon 1. (J:211733)