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The tTA open reading frame was introduced into the second exon of the human PMP22 gene on YAC 49G7 such that the start of translation of the PMP22 gene is used to start the tTA ORF. The PMP22 genen on the YAC is disrupted and is not expressed. tTA is expressed in Schwann cells. (J:69545)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
