The transgene comprises a 60-kb DNA fragment containing the bovine prion protein gene (PRNP) (GenBank: AJ298878) derived from clone D18330 of bovine bacterial artificial chromosome (BAC) library 750 from the German Resource Center for Genome Research (RZPD, Resourcenzentrum Primrdatenbank). Mice bearing this transgene express bovine prion protein from its own promoter in brain and other tissues. (J:82809, J:232471)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/NIco
--
Insertion
--
--
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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