A floxed neomycin resistance cassette replaced exons 2 through 10. Cre-mediate recombination removed the selection cassette. RT-PCR confirmed transcript expression below detectable limits in the spleen, heart, kidney, liver and lung. (J:229059)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count