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The targeted construct inserted into the locus a splice acceptor, CAG promoter, floxed stop cassette, mouse cDNA encoding an amino acid substitution of alanine for serine at position 112 (S112A), FRT-flanked IRES and EGFP reporter gene and a polyadenylation sequence. Flp-mediated recombination removed the neomycin resistance cassette. (J:220179)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
