Exon 3, which encodes 39 amino acids responsible for homodimerization, tetramer formation and manganese binding, was flanked by loxP sites. A floxed neomycin resistance cassette was inserted upstream of exon 3. (J:98289)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count