The transgene was designed with (from 5' to 3') a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), a loxP-flanked fusion protein containing an enhanced green fluorescent protein sequence (EGFP), and a polyadenylation (pA) signal, a mouse tumor necrosis factor (Tnf) cDNA followed by a two pA signals. (J:231511)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count