The transgene contains a rat neuron-specific enolase (Eno2) promoter (including regulatory sequences: exon 1, intron 1, and 6 bp of exon 2) directing expression of a human solute carrier family 29 (nucleoside transporters), member 1 (SLC29A1 or ENT1) cDNA followed by a polyA signal. The SLC29A1 transcription initiation codon is in-frame with exon 2. Expression is detected in the cerebral cortex, striatum, hippocampus and cerebellum. RNA samples from skeletal muscle, heart, liver, kidney and lung are negative for transgene expression. (J:231362)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count