The transgene contains a rat neuron-specific enolase (Eno2) promoter (including regulatory sequences: exon 1, intron 1, and 6 bp of exon 2) directing expression of a human solute carrier family 29 (nucleoside transporters), member 1 (SLC29A1 or ENT1) cDNA followed by a polyA signal. The SLC29A1 transcription initiation codon is in-frame with exon 2. Expression is detected in the cerebral cortex, striatum, hippocampus and cerebellum. RNA samples from skeletal muscle, heart, liver, kidney and lung are negative for transgene expression. (J:231362)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CD-1
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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