The targeting construct introduced into the locus a CAG promoter, floxed neomycin/STP cassette, modified murine cDNA in which nucleotide substitutions results in the amino acid substitution of glutamic acid for lysine at position 320 (K320E), and an FRT-flanked IRES-EGFP reporter gene. (J:225849)
Basic Information
Insertion, Nucleotide substitutions
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count