The targeting construct introduced into the locus a CAG promoter, floxed neomycin/STP cassette, modified murine cDNA in which nucleotide substitutions results in the amino acid substitution of glutamic acid for lysine at position 320 (K320E), and an FRT-flanked IRES-EGFP reporter gene. (J:225849)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion, Nucleotide substitutions
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9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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