This allele from project Clstn2-7604J-M4612 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CCAACGGTGTGCTTGGAAGG, CCTGTCGCCCACCTTCTCCC, TTGTAGATCCAGCTCTGTCG and TCACCATGCTCAACTAGACT, which resulted in a 445 bp deletion spanning exon 3 beginning at Chromosome 9 negative strand position 97,583,831 bp, GTCTAGTTGAGCATGGTGAAT, and ending after CACCAACGGTGTGCTTGGAA at 97,583,387 bp (GRCm38/mm10). This mutation deletes exon 3 and 249 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 80 and early truncation 6 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count