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The transgene consists of a Ctss cDNA sequence under the control of a modified human ACTA1 promoter, which is active in skeletal muscle. Western blot analysis confirms overexpression in multiple skeletal muscles that are predominantly fast-twitch, with lower levels of expression in soleus (slow-twitch). Founder line 1 is the higher expressing transgenic line. (J:230788)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
