A targeting vector was used to insert a stop codon in each frame immediately downstream of the endogenous translational start codon. An IRES-EGFP was placed downstream of the endogenous regulatory sequences and a floxed PGKneo were also inserted. Cre-mediated recombination removed the neomycin resistance cassette. (J:223351)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count