The transgenic mouse strain was made using small plasmid transgenesis. A 5.89-Kbp upstream region of Mbp (promoter fragment) was used for driving iCreERT2 with parts of Plp exons 6 and 7 downstream, followed by a poly(A) sequence. Two founders were obtained, and as both had similar expression patterns and intensity, one was selected for further characterization. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:229987)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count