The transgenic mouse strain was made using small plasmid transgenesis. A 5.89-Kbp upstream region of Mbp (promoter fragment) was used for driving iCreERT2 with parts of Plp exons 6 and 7 downstream, followed by a poly(A) sequence. Two founders were obtained, and as both had similar expression patterns and intensity, one was selected for further characterization. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:229987)
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基础信息

模型ID
品系来源
等位基因类型
突变
遗传方式
基因表达
相关疾病
参考文献
(C57BL/6 x CBA)F1
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Insertion
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1

表型特征

标签摘要:
hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
观察到的表型
N: 正常表型
(#): 上标括号内为相关疾病数量
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