The transgene was designed to have the 12.4 kbp promoter fragment from the mouse villin 1 gene (Vil1) with an enhanced green fluorescent protein coding sequence (EGFP). This transgenic founder line 106 has the highest intensity of EGFP expression in the duodenum with progressively diminished expression in the ileum and colon. EGFP is expressed in all epithelial cells throughout the small and large intestine, with no reported evidence of mottled or variegated expression. (J:135613)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F2
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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