The targeting constructs introduced into exon 3 6 bp downstream of the translation initiation sequence a lacZ reporter gene and a floxed neomycin resistance cassette. Immunohistochemistry confirmed the absence of protein expression in the knee joint. (J:222369)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count