The transgenic vector was constructed using the RP24-291E22 BAC from CHORI containing the entire murine Il21 gene. The iCre replaced exons 1-2 of Il21 downstream of the promoter. Founder mice line G was established and maintained in breeding transgenic mice. (J:230488)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count