This allele from project Rfc2-7423J-F4989 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CCACCTTGCCAGAATCTGCA, CAACACACAGAGGCTAAGCC, ATTGCTATGTCAACCCCACG, and TCGTGGGGTTGACATAGCAA, which resulted in a 413 bp deletion spanning exon 2 beginning at Chromosome 5 positive strand position 134,586,788 bp, GTGTTGGCATCACAGCTCCACCT, and ending after GGCCTCTATTTTTATTTATTT at 134,587,200 bp (GRCm38/mm10). This mutation deletes exon 2 and 343 bp of flanking intronic sequence including the splice acceptor and donor. This mutation is predicted to cause an amino acid sequence change after residue 33 and early truncation 36 amino acids later. (J:188991)
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基础信息

模型ID
品系来源
等位基因类型
突变
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相关基因
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参考文献
C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
1
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标签摘要:
hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
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N: 正常表型
(#): 上标括号内为相关疾病数量
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