The promoter, exon 1 and exon 2 were floxed. Flp-mediated recombination removed the puromycin resistance cassette and left and FRT site upstream of the second loxP site in intron 2. (J:230105)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count