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Most of the exon 1 coding region and the exon 1 to intron 1 junction is replaced by an in-frame EGFP-bGH-pA-FRT-neo-FRT cassette via homologous recombination. Flp-mediated recombination removed the FRT-flanked neo cassette. Although predicted to be a loss-of-function allele, both heterozygous and homozygous mice exhibit no obvious phenotypic abnormalities. (J:229960)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
