Log In|Sign Up
EN
This allele produced from project TCPR0399 at TCP by injecting Cas9 mRNA and four guide RNAs with the spacer sequences CAGCCTCATCGGACGGAGTG, TTGGTCGATGTGTCTTGTAG, ACTCCTTATTCTCCTCACGG, and GCCGGCTCCAGTAAATAATT. This resulted in a 289 bp deletion from Chr6:142413819 to 142414107 & 31 bp deletion from Chr6:142414151 to 142414181, encompassing ENSMUSE00000608439 & ENSMUSE00000608438. This mutation is predicted to cause a frameshift with amino acid changes after residue 3 and early truncation 27 amino acids later (p.G3Rfs*29). (GRCm38). (J:165963)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
