This allele produced from project TCPR0417 at TCP by injecting Cas9 mRNA and four guide RNAs with the spacer sequences GTGAGCTCGGTCTTGGTTTG, CTTCAGGACGGTGTACTGCC, CAGCTCAGTGTCCTAATCAC, and ATGTCCGTTTGGCAGAATAG. This resulted in a 5-bp deletion from Chr10:18785183 to 18785187, a 1,713-bp deletion from Chr10:18783181 to 18784893 deleting majority of ENSMUSE00000403934 including splice donor (single exon ORF) & 6-bp deletion from Chr10:18783159 to 18783164 (GRCm38). (J:165963)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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