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This allele produced from project TCPR0264 at TCP by injecting Cas9 mRNA and one guide RNA with the spacer sequence GAAAGATAAAGAAGCTGTCG. This resulted in an indel comprised of an 8-bp deletion on Chr15 from 8176272 to 8176279 bp (GRCm38) and a 4-bp insertion of AGAA into exon 6 (ENSMUSE00000337126). This mutation is predicted to cause a frameshift with the animo acid changes after residue 160 and early truncation 19 amino acids later (p.W161Kfs*21). (J:165963)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
