This allele produced from project TCPR0315 at The Centre for Phenogenomics by injecting Cas9 D10A mRNA and four guide RNAs having spacer sequences AGCCGCTCGGCCCCGCGCTA, AGCGGAGGGCGTCTCGCCCT, TGTACTCCGTGTCGAAGCGT and AGGCTGCAACAATCAGTATC. This resulted in an indel comprised of a 42-bp deletion on Chr 4 from 155992472 to 155992513 with a 2-bp insertion of CC (GRCm38). (J:165963)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Insertion, Intragenic deletion
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1
5
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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