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The transgene contains the tetracycline response element, comprising seven copies of the tetracycline operator (tetO) sequence, flanked on each side by a cytomegalovirus (CMV) minimal promoter and the coding sequence for either gap junction protein, alpha 1 (Gja1, also called Cx43) or enhanced green fluorescent protein (EGFP), each followed by the beta-globin insulator sequence. Expression of the tetracycline transactivator from a second transgene result in the expression of both Gja1 and the EGFP reporter. (J:82809, J:130466)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
