The targeting construct introduced upstream of the start codon a cre recombinase gene fused with EGFP (cre/EGFP), a myc tag, nuclear localization signal at the N-terminus and polyadenulation sequence. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette introduced downstream of the fusion gene. (J:221577)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count