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The transgene was designed to have the human CD68-IVS-1 promoter (~1 kbp of human CD68 5' flanking sequence with the 83 bp first intron enhancer [IVS-1])direct expression of an AMP-activated protein kinase catalytic alpha 1 cDNA sequence harboring the constitutively active threonine 172 to aspartic acid amino acid substitution (T172D) with amino-terminal myc epitope tag, all followed by a polyadenylation signal. The investigator does not indicate organism source of the expressed gene (e.g. human, mouse, etc.). (J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
