A loxP site was inserted upstream of exon 2 and a loxP site and FRT flanked selection cassette was inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the selection cassette. (J:221572)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count