A PGK/Neo cassette flanked by two FRT sites and loxP sequence were inserted 400 bp upstream of exon 2 and the second loxP sequence was placed at 278 bp downstream of the stop codon. Cre-mediated recombination removed the PGK/Neo cassette and exon 2. (J:239574)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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