In intergenic control region 1 (IGCR1) the first CCCTC-binding factor (CTCF)-binding element (CBE1) was replaced with scrambled sequence that does not bind CTCF. A floxed neo cassette was also inserted between the two CBEs and subsequently removed by cre mediated recombination. (J:220021)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion, Nucleotide substitutions
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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