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The transgenic construct contains Ighm (IgM) and Ighd (IgD) heavy chain genes of islet-derived peripherin-specific B cell hybridoma H280. The transgene also contains a constant region component allowing expression of PerH as an IgM/D isotype of the IgHa allotype rather than an IgHb allotype naturally characterizing NOD mice. (J:274578)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
