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A loxP site and FRT-flanked neomycin cassette are introduced into intron 5 followed by a loxP site placed in intron 7. Flp-mediated recombination removed the FRT-flanked neo cassette. Cre-mediated recombination removed exons 6 and 7. Western blot anaylsis on nine tissues confirmed that no protein was expressed in mutant mice. (J:234905)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
