A loxP site and FRT-flanked neomycin cassette are introduced into intron 5 of the gene, a second loxP site is placed in intron 7. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 6 and 7 flanked by loxP sites. (J:234905)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count