LoxP sites were inserted at positions 63,255,283 and 63,256,404 (GRCm38/mm10) flanking the mouse Notch Myc enhancer (N-Me) along with an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the enhancer sequence. (J:227747)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
Insertion, Intergenic deletion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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